Generic Vibramycin (Doxycycline 100mg) consists of doxycyclini hydrochloridum. Comparing with the other tetracyclines has much better absorbency in the body (when orally administered). Prolonged antibacterial effect that allows to achieve a therapeutic effect when assigning once daily. Provided primarily through the kidneys by glomerular filtration, slowly, so in the treatment of possible cumulation.
Indications: bronchopulmonary infections, urinary and digestive systems, purulent skin and subcutaneous tissue, and others. Due to the fact that doxycycline scarcely penetrates the blood-brain barrier, its use in bacterial meningitis is inappropriate.
- Doxycycline is an semisynthetic antibiotic, oxytetracycline derivative. It is characterized by a wide spectrum of action (like other tetracyclines), but not active against viruses, Pseudomonas aeruginosa, Proteus, fungi.
- Gelatin capsules of 0.05 and 0.1 g daily dose of an antibiotic for children from 8 to 12 years – 4 mg / kg on the first day and 2 mg / kg in the next few days (these days in severe infections daily dose can be maintained at 4 mg / kg).
Children under the age of 12 years, an antibiotic administered in the same dose as adults: the first day of 0.2 grams in one go, or 0.1 g 2 times a day (12 hours), in the following days a daily dosage of 0, 1 g once. It is recommended to take the drug after a meal, drink milk or yogurt.
Photosensitivity with symptoms of dermatitis, allergic reactions.
Not indicated for children up to 8 years and persons with hypersensitivity to tetracyclines. Antibiotic used with caution in the human liver and kidneys (cumulative effect is possible). Patients who received anticoagulants dose should be reduced, because the drug inhibits the activity of plasma prothrombin.